New drug gives longer life to cystic fibrosis sufferers

People with cystic fibrosis could now live longer after scientists announced the discovery of a new drug, the first major breakthrough in 10 years.

Sydney clinical trials of Bronchitol have shown the drug increased lung capacity. Announcing the results of the trial yesterday, The Children's Hospital, Westmead cystic fibrosis unit director Dr Peter Cooper said it was the first drug in a decade to show results.


"The Bronchitol trial has shown a genuine increase in lung function for CF patients using the drug," he said.

"With better clearance of mucus from the lungs, CF patients are likely to live a better and longer life."

One child is born in Australia every four days with cystic fibrosis, a lung condition that can cause respiratory failure. It is the world's most commonly occurring genetically inherited disease, affecting 75,000 people worldwide.

Sufferers experience repeated lung infections and blockages which cause irreversible damage and eventually respiratory failure.

More than 40 countries took part in the trial, sponsored by the Australian pharmaceutical company Pharmaxis.

The drug is a dry powder that works to break the cycle of lung infection, inflammation and damage.

During the trial, lung capacity of those involved increased by 6 per cent.

Dr Cooper said it was hoped the drug could extend a person's life beyond the average of 37.

"If approved Bronchitol will be among the first inhaled dry powder products registered for cystic fibrosis and offers patients a treatment option with less drug administration time and the equipment maintenance issues associated with nebulised liquids," Dr Cooper said.

For Georgia Jones, 11, who was born with cystic fibrosis and took part in the trial, the drug has changed her life. Her family noticed a distinct change when she began taking Bronchitol.

"The results speak for themselves," mum Sue Georgias said.

"When our trial period ended we made a formal request for Georgia to continue due to the benefits achieved."

Source : www.news.com.au